Testosterone therapy improves sexual function in older men
Older men with low libido and low testosterone levels showed more interest in sex and engaged in more sexual activity when they underwent testosterone therapy, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.
The study is the largest placebo-controlled trial in older men conducted on the subject to date. The sexual function study is part of the Testosterone Trials, a series of seven studies examining the effectiveness of hormone therapy in men who are 65 or older, who have low testosterone levels and are experiencing symptoms of testosterone deficiency. The research is supported primarily by the National Institutes of Health.
Testosterone is a key male sex hormone involved in maintaining sex drive, erectile function and sperm production. The Endocrine Society's Clinical Practice Guideline recommends using testosterone therapy to treat men with symptoms of androgen deficiency and low levels of testosterone.
Androgen deficiency occurs when a man has consistently low levels of testosterone and resulting symptoms such as sexual dysfunction.
In the past 15 years, use of testosterone therapy has rapidly expanded among men. Testosterone levels decline as men age, and some men develop low testosterone levels and symptoms.
Since 2000, the number of men beginning testosterone therapy has almost quadrupled in the United States, according to a 2014 study published in The Journal of Clinical Endocrinology & Metabolism.
"Our findings indicate low testosterone is one cause contributing to reduced libido and erectile dysfunction in older men," said the study's first author, Glenn R. Cunningham, MD, of Baylor College of Medicine and Baylor St. Luke's Medical Center in Houston, TX.
"Men experiencing these symptoms should be evaluated for testosterone deficiency."
The study was designed to investigate the effectiveness of testosterone therapy. It was not large enough or long enough to address issues related to cardiovascular events or clinical prostate cancer.